STI Publications - View Publication Form #16586

Back to Search Results Print
Publication Information
Title Evaluation of Preoperative and Intraoperative Mobile Gamma Camera Imaging in Sentinel Lymph Node Biopsy for Melanoma Independent of Lymphoscintigraphy
Abstract Background and Objectives: Sentinel lymph node biopsy (SLNB) is standard practice for staging cutaneous melanoma. High false negative rates have increased interest in adjunctive techniques for localizing SLNs. Mobile gamma cameras (MGCs) represent potential tools to enhance SLNB performance. Methods: Twenty eligible melanoma patients underwent 99mTc sulfur colloid injection and standard lymphoscintigraphy with a fixed gamma camera (FGC). A survey using a 20 cm square MGC, performed immediately preoperatively by the study surgeon, was used to establish an operative plan while blinded to the FGC results. Subsequently, SLNB was performed using a gamma probe and a novel 6 cm diameter handheld MGC. Results: A total of 24 SLN basins were detected by FGC. Prior to unblinding, all 24 basins were identified with the preoperative MGC, and the operative plan established by preoperative MGC imaging was confirmed accurate by review of the FGC images. All individual SLNs were identified during in
Author(s) Joshua Judge, Kosta Popovic, Gina Petroni, Brian Kross, John McKisson, Jack McKisson, Drew Weisenberger, Alexander Stolin, Stan Majewski, Patrice Rehm, Craig Slingluff Jr., Mark Williams, Lynn Dengel
Publication Date May 2023
Document Type Journal Article
Primary Institution University of Virginia, Charlottesville, VA
Affiliation Exp Nuclear Physics / Technical Support Groups / Detector
Funding Source Nuclear Physics (NP)
Proprietary? No
This publication conveys Technical Science Results
Document Numbers
JLAB Number: JLAB-PHY-21-3366 OSTI Number: 1997946
LANL Number: Other Number: DOE/OR/23177-5189
Associated with an experiment No
Associated with EIC No
Supported by Jefferson Lab LDRD Funding No
Journal Article
Journal Name Journal of Surgical Research
Refereed No
Volume 285
Issue
Page(s) 176-186
Attachments/Datasets/DOI Link
Document(s)
DOI Link
Dataset(s) (none)
Back to Search Results Print